Description
CJC-1295 DAC was first introduced in 2005 by the Canadian biotechnology company ConjuChem. Unlike peptides of the GHRP group, CJC-1295 DAC releases growth hormone evenly in small amounts without sharp jumps of GH in the blood and has a similar effect to growth hormone. After a single injection of CJC-1295 DAC, the concentration of the hormone in the blood increases 2-10 times within six days. It is used by athletes for various purposes of increasing performance.
Characteristics:
- Active half-life (hours): from 6 to 8 hours
- Group: Peptide hormone
- Subgroup: Injectable/powdery
- Dosage: 2 mg (2000 mcg)
- Application (men): 1000 mcg for 3-4 days.
- Product packaging: 1 bottle
- Retains water: Yes
- Flavoring: None
One of the main advantages of CJC-1295 DAC compared to the widely used analog GRF (1-29) (synonyms: CJC-1295 w/o, without or without DAC) is a long half-life (up to two weeks). CJC-1295 DAC binds to plasma proteins (albumins), which leads to a significant increase in the duration of action due to the addition of lysine associated with a non-peptide DAC molecule (Drug Affinity Complex).
Mechanism of action of CJC-1295 DAC
The drug acts on the nuclei of the anterior lobe of the pituitary gland and stimulates the secretion of growth hormone, mainly by means of cAMP of the dependent pathway. The substance binds to GHRH receptors, which belong to the group of G-protein coupled receptors.
Effects of receiving CJC-1295 DAC
Studies have shown that it has similar effects to growth hormone:
- increase in strength
- muscle growth
- fat burning
- improvement of skin quality (smoothing of wrinkles)
- increase in bone density
- strengthening of ligaments and joints
- positive effect on sleep
During the course, there are characteristic sensations of muscle swelling.
CJC-1295 DAC course in bodybuilding
After a single injection of CJC-1295 DAC, the concentration of the hormone in the blood increases by 2-10 times by the 6th day, the concentration of IGF-I increases by 1.5-3 times by the 10th day. The half-life is 6-8 days. After several injections, the level of insulin-like growth factor-1 (IGF-1) remains elevated for a month. The average dose is 30-60 micrograms per kg of body weight, once a week.
To maintain the optimal concentration, it is expedient to introduce the peptide 2 times a week, since by the fifth day it drops to ineffective. We will also give graphs of the use of different dosages of the drug, which show that the optimal concentration of IGF-1 is observed at a dose of 60 μg/kg (approximately 2000 μg, twice a week), and when the dose is increased to 125 μg/kg, the concentration of IGF-1 practically does not increases
Thus, the following protocol can be considered optimal: 1000-2000 mcg (1 or 1/2 bottle) twice a week. In addition to training, do not forget to follow a proper diet and take sports nutrition to achieve your goal.
Combined course of taking the drug
It has been well proven and precisely established that the simultaneous administration of GHRH (for example, CJC-1295) and GHRP (for example, GHRP-6 or GHRP-2) leads to a synergistic effect. These peptides have a potentiating effect on each other. In other words, with the introduction of one CJC-1295, we will get a stimulating effect of 2 points. With the introduction of only GHRP-6, we will get an effect of 4 points. When introducing both substances at the same time, we will get an effect not of 6 points (additive action 2+4=6), as expected, but of 10 points – more than the sum of each separately (potentiating action 2+4=10). Thus , we get not only a greater anabolic response, but also can save money.
Despite the fact that the natural pulsation of GH is preserved when CJC-1295 is administered, it does not cause an increase in these peaks, increasing only the basal level of GH, thus creating a female-type concentration pattern with a smaller anabolic response. Moreover, GHRH is effective only when somatostatin levels are low. Therefore, the combination of CJC-1295 and GHRP-6 or GHRP-2 allows you to preserve the natural curve and adjust the time and height of the concentration peaks.
Optimal combined course
- GHRP-6 or GHRP-2 100 mcg three times a day.
- CJC-1295 DAC 1000 mcg twice weekly.
- The duration of the course is 8-12 weeks.
In terms of effectiveness, it is comparable to a cycle of growth hormone at 15 ED/day, while the cost is several times lower.
Side effects
CJC-1295 DAC is a peptide and does not cause side effects associated with anabolic steroids. The most common side effects attributed to CJC-1295 DAC are excessive water retention and weakness.
For more information, please read the instructions.
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