Description
Many athletes take Genotropin also because this drug helps to accelerate the rehabilitation of the body after surgery and injuries received during training.
The effect of taking Genotropin
Genotropin Pfizer has proven itself well not only in medicine, but also in sports. According to the results of the conducted studies, the somatropin hormone has a positive effect on the speed of the lipolysis process in subcutaneous fat deposits and visceral tissue, which also contains fat. During the course of taking this medicinal product:
- increase in HDL concentration,
- decrease in LDL level.
Achieving the anabolic effect is due to the processes of hypertrophy and hyperplasia occurring in the muscles. Because the price of Genotropin is in some cases lower than that of other similar drugs, it is often purchased to achieve the effect of increasing protein synthesis and activation of stem cells.The latter, having completed its growth and differentiation, merge with the existing muscle fibers.
Key effects that can be achieved using this drug are considered to be:
- makes the body more beautiful and toned,
- increasing endurance and increasing peak strength,
- the muscular relief grows.
The course of taking Genotropin for athletes
The GR course is suitable for men and women over 20 years of age. This is due to the possibility of asymmetric bone growth in young people. With its help, more relief muscles are obtained.
Before ordering Genotropin, it is necessary to understand what amount of the drug is needed for the course of achieving the desired result. Specialists recommend taking no more than 4,000 IU of Genotropin per week, and the course of treatment should not exceed 3-6 months.
There are other recommendations that require an individual approach to choosing a dose, because this indicator is influenced by various factors:
- dosage of other drugs taken,
- types of drugs.
For example, if you have completed a steroid course, then in this case, the dosage of growth hormone should be higher.
As for the frequency of administration of the drug, bodybuilders use about 1000-1500 IU every 2 days. It should be remembered that scientists have discovered such a regularity that an injection in the amount of 1500 IU leads to a jump in plasma testosterone by approximately 300%, and its level is maintained for up to 6 days. Due to this, it is expedient to inject into the body a little less often 1 dose every 3-4 days.
In case of an acute overdose, hypoglycemia with subsequent progression to hyperglycemia can be observed. If the overdose is prolonged, it will certainly manifest itself as acromegaly or gigantism.
Dosing mode.Method of application and doses of Genotropin
The drug should be prescribed in a dose that will be individual for each person. The injection must be administered subcutaneously, changing the injection site every time. This will help prevent lipoatrophy. Despite the fact that the price of Genotropin is as reasonable as possible, experts recommend starting with a dose of 0.15-0.30 mg/day. Specialists should calculate the final dosage, because age and gender will affect this number. The maintenance dose practically never exceeds 1.3 mg. Women may need a higher dose of this drug. There is a risk that women receiving hormone replacement therapy will receive insufficient treatment.
Due to the fact that with age, the growth hormone is produced more and more poorly, the dose of the drug is reduced. Due to the side/clinical effects and the concentration of insulin-like growth factor, type 1 in the blood, it is possible to choose the dose more correctly and more efficiently.
Indications Application of Genotropin
Many people are interested in how to take Genotropin not only in a sports environment, but also for medical purposes. Indications for use differ for children and adults.
Where are you:
- slowed growth due to low hormone production,
- stunted growth due to Shereshevsky-Turner syndrome,
- growth problems due to chronic kidney failure,
- if the child has not reached the usual growth rate by the age of 2,
- problematic growth in children who have Prader-Willi syndrome.
Adult:
- Congenital or acquired during life GR deficiency, which meets one of the criteria:
- the patient has only a lack of growth hormone or in combination with insufficient production of some other hormones. As a result, a disease of the hypothalamus or pituitary gland may be observed,
- children who had a lack of growth hormone in childhood for congenital or acquired reasons.
Pregnancy and lactation:
If we talk about the clinical experience of use in pregnant women, then it is very limited. As for experiments on animals, no negative or harmful effect on the fetus was revealed. Considering this factor, it is impossible to say with certainty that it is safe to buy and use Genotropin. Doctors do not recommend using the drug during pregnancy and breastfeeding.
If the pregnancy proceeds normally, the pituitary growth hormone slows down its production by the 20th week and is replaced by the placental hormone at the beginning of the third trimester of pregnancy. Thus, replacement therapy with Genotropin in the 3rd trimester is unlikely.
Genotropin side effect
Patients suffering from growth hormone deficiency have a lack of fluid, and if you start a Genotropin course, this indicator will quickly recover. Side effects of Genotropin often take the form of fluid retention in the body. For this reason, various edemas, myalgia and paresthesia are observed. Similar phenomena in most patients are expressed rather weakly, and their manifestation is observed in the first months of treatment. After the withdrawal of the drug, side effects decrease. The frequency of their occurrence directly depends on the dosage of Genotropin and the age of the patient.
Specialists also observe such reactions as itching and rash at the injection site.Soreness and numbness of the area where the drug was injected are not excluded. Izvestny cases of lowering the concentration of cortisol in the blood.
Cases of leukemia are very rarely observed among children suffering from growth hormone deficiency and receiving special therapy with Genotropin. It is worth noting that the frequency of leukemia development is similar in children who do not have a low level of growth hormone.
In addition, the following effects may be observed:
- the appearance of benign or malignant tumors,
- metabolic disorders,
- paresthesia benign intracranial hypertension in children and adults,
- arthralgia, myalgia, muscle stiffness.
An allergic reaction, which manifests itself as a subcutaneous rash and itching, insomnia and headache, and the development of swelling of the optic nerve, cannot be ruled out. There is epiphysiolysis of the femoral head.
Contraindications to use
The cost of the drug Genotropin is as adequate as possible, but as for the contraindications, they are the same as for any other medical drug. The first is hypersensitivity to all or a specific component of Genotropin. Regardless of the dosage of Genotropin, it is strongly not recommended to be taken by people with tumor growths. This includes uncontrolled growth of benign intracranial tumors. Even if you have to take this drug, complete antitumor therapy before the course begins. It is inadmissible to give injections to people who have a critical state that appeared on the background of multiple injuries and/or in the case of acute respiratory failure.
With replacement therapy with growth hormone, the appearance of a critical state is sometimes observed.In this case, it is worth evaluating the continuation of the course according to the risk-benefit criterion. The drug should not be used in case of severe forms of obesity, when the ratio of body weight to height is more than 200%.
Interaction of Genotropin with other drugs
With ACTH deficiency, it is necessary to carefully adjust GCS replacement therapy to avoid a suppressive effect on the growth factor. The suppressive effect of somatropin on the conversion of cortisone to cortisol is not excluded. It can also contribute to the detection of previously unknown adrenal insufficiency of central origin. In some cases, it affects the effectiveness of low doses of GCS.
Somatropin leads to an increase in the clearance of those compounds that are metabolized by P4503A4. The significance of such an effect was not studied.
Women who receive oral estrogens may need to increase the dose of somatropin to obtain the desired effect.
Patients who take levothyroxine sodium may experience the effect of moderate hyperthyroidism. Because of this, it is recommended to conduct a study of the function of the thyroid gland before the start of the Genotropin course and when changing its dosage.
Storage conditions of the drug. Expiry date
It is necessary to store Genotropin at a temperature of 2-8 degrees Celsius in a place inaccessible to children. The finished solution is stored in the refrigerator at a similar temperature for no more than 4 weeks. It is forbidden to freeze the cartridge and the finished solution. The shelf life is 3 years.
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