Chorionic Gonadotropin (2000 iu)


Chorionic Gonadotropin from Cygnus Pharma is one of the most popular means for PCT. Its action is based on synthetic hCG, which is naturally synthesized in the female body during pregnancy. In bodybuilding, chorionic gonadotropin is usually used to prevent androgenic side effects and normalize the hormonal background.



This HCG/hCG (human chorionic gonadotropin) is available in injection form (vials of 2000 iu) and is intended for intramuscular administration. The scheme of reception and dosage of the drug is selected individually, based on the duration of the course and the steroid being taken.

Recent studies have shown the complete ineffectiveness of the use of this drug when used internally as a food additive.

Physiology of gonadotropin

In the body, the regulation of the gonadotropin level occurs according to the feedback mechanism in the hypothalamus-pituitary-testis axis:

  • gonadoliberin is produced in the hypothalamus and stimulates the release of gonadotropic hormones,
  • gonadotropins are produced in the pituitary gland and normally stimulate the work of the testicles, with their deficiency testicular atrophy occurs,
  • testosterone and anabolic steroids inhibit the production of gonadoliberin and gonadotropins, resulting in testicular atrophy.

Thus, in bodybuilding, with long-term use of anabolic steroids, it is necessary to additionally introduce gonadotropin hormone (chorionic gonadotropin) in order to prevent testicular atrophy.

Effects of taking Chorionic Gonadotropin

  • stimulates the synthesis of sex hormones in the testicles, so it has the same range of effects as testosterone,
  • stimulates spermatogenesis,
  • enhances the development of genital organs and secondary sexual characteristics,
  • in women, it stimulates the production of progesterone by the corpus luteum, provokes ovulation, and supports the development of the placenta.

Application and dosage of Chorionic Gonadotropin

In bodybuilding, perhaps only one property of gonadotropin is valued: increasing the secretion of sex hormones (testosterone) by the testicles. Because of this, gonadotropin is used as a means of preventing testicular atrophy and as a component of PCT.

Currently, the pharmaceutical industry produces a huge number of drugs containing hCG. After intramuscular administration, the drug is well absorbed. The half-life is several hours, but the effect of one injection lasts for 5-6 days.

The powder dissolves well in the solution. The resulting mixture should be administered intramuscularly or subcutaneously. If you did not use all the liquid, then the rest should be placed in the refrigerator. Dry hCG should be stored in a dark place at a temperature not higher than +25 degrees Celsius.

If the duration of the course does not exceed 5-6 weeks, 1 drug is used in small doses, then there is no need for gonadotropins. If the duration of the course is more than 6 weeks (8-12 weeks), the dosage is high, 2 or more drugs are used: at least, in the last 3-5 weeks of the course, perform 2 injections of gonadotropin per week at 250-500 IU to prevent testicular atrophy. The administration stops after almost complete withdrawal of the anabolic drug, then the post-course therapy begins. On multi-month courses, gonadotropins are administered continuously, 3-5 weeks after 1-2 weeks (it is necessary to take a break of at least 1-2 weeks to prevent desensitization).According to the latest scientific data, this scheme is considered optimal, as it allows you to preserve the function of the testicles and promotes the most complete recovery after the course.

Side effects

When taking hCG, the same side effects may occur as when taking testosterone. The use of gonadotropin in large doses or for a long time leads to suppression of the secretion of gonadotropin-releasing hormone, as a result of which the function of the physiological axis of the hypothalamus-pituitary-testis is disturbed. Large doses (2000-5000 IU) are not recommended for longer than 20 days, although according to Michael Scally, M.D. In the presented series of studies, testicular desensitization does not occur if the dosage does not exceed 500 IU or hCG is administered less than 3 times a week. This protocol can be considered safe even for 1-2 months.

The use of hCG for anabolic purposes is not justified and is dangerous for health. Chorionic gonadotropin is less effective compared to anabolic steroids, as a result of which, in order to obtain a good effect, it is necessary to use it in large doses (more than 4000 IU per week), which can cause irreversible disturbances in the physiological axis of the hypothalamus-pituitary-testicles. Due to this fact, many articles negatively comment on hCG, forgetting about its true purpose.


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