Pregnyl 1500 iu (3 bottles of hCG and 3 bottles of solvent)


Pregnyl 1500 iu from MSD is increasingly in demand among athletes every year. Its use in sports is justified for various tasks, but it is usually used as a support after a course of steroids (to promote the development of physical fitness and prevent side effects).



Pregnyl 1500 iu (human chorionic gonadotropin) is a drug that is a hormone produced by the placenta during pregnancy. It has similar properties to luteinizing hormone and follicle-stimulating hormone (gonadotropic hormone, produced mainly in the pituitary gland).

Physiology of gonadotropin

In the body, the regulation of the gonadotropin level occurs according to the feedback mechanism in the hypothalamus-pituitary-testis axis:

  • gonadoliberin is produced in the hypothalamus and stimulates the release of gonadotropic hormones,
  • gonadotropins are produced in the pituitary gland and normally stimulate the work of the testicles, with their deficiency testicular atrophy occurs,
  • testosterone and anabolic steroids inhibit the production of gonadoliberin and gonadotropins, resulting in testicular atrophy.

Thus, in bodybuilding, with long-term use of anabolic steroids, it is necessary to additionally introduce gonadotropin hormone (chorionic gonadotropin) in order to prevent testicular atrophy.

Effects of taking Pregnyl

After the introduction of chorionic gonadotropin into the body, this substance begins to act similar to the luteinizing hormone. The main effects of this drug include:

  • stimulates the synthesis of sex hormones in the testicles, so it has the same range of effects as testosterone,
  • stimulates spermatogenesis,
  • enhances the development of genital organs and secondary sexual characteristics,
  • in women, it stimulates the production of progesterone by the corpus luteum, provokes ovulation, and supports the development of the placenta.
  • Women use gonadotropins in the presence of the following diseases:

  • infertility
  • ovarian dysfunction,
  • ovulation induction,
  • amenorrhea,
  • Violation of follicle maturation.
  • For medical purposes, chorionic gonadotropin is used by men and women with reproductive health problems. Before starting to take this drug, it is necessary to consult a doctor.

    Application and dosage of Pregnyl

    In bodybuilding, perhaps, only one property of gonadotropin is valued – increasing the secretion of sex hormones (testosterone) by the testicles. Because of this, gonadotropin is used as a means of preventing testicular atrophy and as a component of PCT.

    The use of HCG for anabolic purposes is not justified and is dangerous for health. Chorionic gonadotropin is less effective compared to anabolic steroids, as a result of which, in order to obtain a good effect, it is necessary to use it in large doses (more than 4000 units per week), which can cause irreversible disturbances in the physiological axis of the hypothalamus-pituitary-testicles. Due to this circumstance, many articles speak negatively about HCG, forgetting about its true purpose.

    Application protocols by Michael Scally MD and Eric Potratz

    If the duration of the course does not exceed 5-6 weeks, 1 drug is used in small doses, then there is no need for gonadotropins. If the duration of the course is more than 6 weeks (8-12 weeks), the dosage is high, 2 or more drugs are used: at least, in the last 3-5 weeks of the course, perform 2 injections of gonadotropin per week at 250-500 units to prevent testicular atrophy.Administration is stopped after almost complete elimination of the anabolic drug, then post-course therapy begins. In multi-month courses, gonadotropins are administered continuously for 3-5 weeks after 1-2 weeks (it is necessary to take a break of at least 1-2 weeks to prevent desensitization). According to the latest scientific data, this scheme is considered optimal, since it allows you to preserve the function of the testicles and promotes the most complete recovery after the course.

    If HCG was not used during a long or "heavy" course, then it should be included in post-course therapy, but then it should be used only at the beginning of PKT. The blust protocol based on the book by William Llewellyns (Program for Wellness Restoration) is most often used, supported by clinical trials, according to which HCG is recommended to be used as part of post-course therapy at 2000 IU every other day for 20 days to restart the hypothalamus-pituitary-testicular arc, such a scheme extremely not recommended in the absence of complications.

    Side effects

    When taking HCG, the same side effects may occur as when taking testosterone. The use of gonadotropin in large doses or for a long time leads to suppression of the secretion of gonadotropin-releasing hormone, as a result of which the function of the physiological axis of the hypothalamus-pituitary-testis is disturbed. Large doses (2000-5000 IU) are not recommended for more than 20 days, although according to Michael Scally, M.D. and according to a series of studies, desensitization of the testicles does not occur if the dosage does not exceed 500 edils of hCG administered less than 3 times a week. This protocol can be considered safe even for 1-2 months.

    The information that gonadotropin can lead to symptoms of pregnancy in men is completely absurd and does not correspond to reality.


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