Description
Spectros 140 iu recombinant human growth hormone (somatropin) of European quality is a protein that is produced almost identically to the basic form of natural human growth hormone. This hormone can stimulate tissue growth, linear growth (growth), as well as the metabolism of proteins, carbohydrates, lipids, and minerals. He approved indications for both adult and pediatric populations. In the United States of America, recombinant human growth hormone is used in pediatrics to treat short stature due to growth hormone deficiency (including idiopathic [due to unknown cause] growth hormone deficiency), Turner syndrome, Noonan syndrome, Prader-Willi syndrome, short stature. deficiency of the homeobox-containing gene (SHOX), chronic renal failure, idiopathic short stature and children small for gestational age.
Medical use
Treatment with exogenous growth hormone is indicated only in limited cases and requires regular monitoring due to the frequency and severity of side effects. GH is used as replacement therapy in adults with GH deficiency in childhood or adulthood (usually as a result of an acquired pituitary tumor). In these patients, the benefits variously included a decrease in fat mass, an increase in muscle mass, an increase in bone density, an improvement in the lipid profile, a decrease in cardiovascular disease risk factors, and an improvement in psychosocial well-being.
Second approved use
GH can be used to treat conditions that cause short stature but are not associated with GH deficiency. However, the results are not so impressive compared to the short growth, which is explained solely by the deficiency of the growth hormone. Examples of other causes of short stature that are often treated with GH include Turner syndrome, chronic renal failure, Prader-Willi syndrome, intrauterine growth restriction, and severe idiopathic short stature. Higher (pharmacological) doses are required for significant acceleration of growth in these conditions, providing blood levels significantly higher than normal (physiological) ones. Despite higher doses, side effects during treatment are rare and vary little depending on the condition being treated.
Features of application
The minimum daily dose is equal to 10 units for experienced athletes, and 5 units is enough for beginners, but it is not administered immediately, but in 2-3 approaches. The course should not be continued for more than 3 months. When completing the course, it is necessary to ask intensively and in a variety of ways, since the drug noticeably accelerates the metabolism.
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